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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
26.67
Human Site:
T542
Identified Species:
39.11
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
T542
N
I
L
Y
A
D
D
T
P
G
A
P
V
K
I
Chimpanzee
Pan troglodytes
XP_508900
901
98668
T671
N
I
L
Y
A
D
D
T
P
G
A
P
V
K
I
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
T542
N
I
L
Y
A
D
D
T
P
G
A
P
V
K
I
Dog
Lupus familis
XP_854926
772
85603
T543
N
I
L
Y
A
D
D
T
P
G
A
P
V
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
T542
N
I
L
Y
A
D
D
T
P
G
A
P
V
K
I
Rat
Rattus norvegicus
Q63531
735
82865
S508
I
L
R
Q
K
F
F
S
E
R
E
A
S
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
N473
N
L
L
F
T
D
E
N
D
N
L
E
I
K
I
Chicken
Gallus gallus
Q5F3L1
789
89022
T546
N
L
L
F
T
D
E
T
D
N
S
E
I
K
I
Frog
Xenopus laevis
P10665
733
82620
S506
I
L
R
Q
K
F
F
S
E
R
E
A
S
S
V
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
V517
S
E
R
E
A
S
A
V
L
Y
T
I
T
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
E751
N
I
M
F
E
N
R
E
D
R
T
V
K
L
I
Honey Bee
Apis mellifera
XP_395099
910
102507
A576
N
I
V
F
A
H
E
A
E
D
S
P
V
K
I
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
D512
N
I
L
F
E
S
I
D
S
S
A
R
L
R
L
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
S513
N
I
L
F
T
D
D
S
D
D
A
E
L
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
I247
A
R
V
Y
T
A
E
I
V
S
A
V
S
H
L
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
A454
Y
I
A
E
L
L
C
A
L
D
S
L
H
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
33.3
40
0
13.3
N.A.
20
46.6
26.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
60
73.3
20
20
N.A.
40
73.3
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
44
7
7
13
0
0
50
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
50
38
7
25
19
0
0
0
0
0
% D
% Glu:
0
7
0
13
13
0
25
7
19
0
13
19
0
0
0
% E
% Phe:
0
0
0
38
0
13
13
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
32
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
7
7
0
% H
% Ile:
13
63
0
0
0
0
7
7
0
0
0
7
13
0
63
% I
% Lys:
0
0
0
0
13
0
0
0
0
0
0
0
7
69
0
% K
% Leu:
0
25
57
0
7
7
0
0
13
0
7
7
13
7
19
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
69
0
0
0
0
7
0
7
0
13
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
32
0
0
38
0
0
0
% P
% Gln:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
19
0
0
0
7
0
0
19
0
7
0
7
0
% R
% Ser:
7
0
0
0
0
13
0
19
7
13
19
0
19
7
0
% S
% Thr:
0
0
0
0
25
0
0
38
0
0
13
0
7
0
7
% T
% Val:
0
0
13
0
0
0
0
7
7
0
0
13
38
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
38
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _